Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Bioflavonoids, sometimes called flavonoids, are a broad class of plant-derived compounds found in fruits and vegetables. Their use in supporting or treating macular degeneration is primarily rooted in traditional and complementary medicine rather than in direct scientific validation. Historically, bioflavonoids have been consumed for their general antioxidant properties, which are thought to help protect cells, including those in the eye, from oxidative stress and damage. This rationale led to their traditional use in eye health, including macular degeneration, a condition where oxidative damage plays a role.

However, scientific evidence specifically evaluating "bioflavonoids (unspecified)" for macular degeneration is limited. Some studies have explored specific flavonoids, such as quercetin or hesperidin, for eye health, but data are inconsistent and often preliminary. Most of the robust clinical trials for macular degeneration, such as the AREDS and AREDS2 studies, have focused on other antioxidants and nutrients (like vitamin C, vitamin E, zinc, copper, lutein, and zeaxanthin), not generalized bioflavonoids. Therefore, while bioflavonoids are traditionally used and are hypothesized to be beneficial due to their antioxidant properties, there is limited direct scientific evidence supporting their efficacy in macular degeneration treatment or prevention.

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