Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Alpha-carotene, like other carotenoids, is an antioxidant found in various fruits and vegetables. Its potential role in supporting or treating Age-related Macular Degeneration (AMD) is based on the hypothesis that antioxidants can help protect the eye’s macula from oxidative damage, a key factor in AMD development. While the Age-Related Eye Disease Study (AREDS and AREDS2) established scientific support for the use of certain antioxidants—particularly beta-carotene, lutein, and zeaxanthin—in reducing the risk of progression to advanced AMD, alpha-carotene itself was not directly studied in these major trials. However, as alpha-carotene is structurally similar to beta-carotene, it is sometimes included in multicarotenoid supplements. Epidemiological studies suggest that higher dietary intake of carotenoids is associated with a lower risk of AMD, but most of this evidence centers on lutein and zeaxanthin, which are selectively accumulated in the retina. Alpha-carotene’s role is less clear, and there is limited direct clinical evidence demonstrating its efficacy in AMD prevention or treatment. Its inclusion in some eye health supplements is largely extrapolated from its general antioxidant properties and data on related carotenoids. In summary, while there is some scientific rationale for including alpha-carotene based on antioxidant theory and its presence in diets linked to lower AMD risk, direct evidence for alpha-carotene’s benefit in AMD is limited, and it is not recommended as a primary intervention.

More about alpha-carotene
More about Macular Degeneration

Other ingredients used for Macular Degeneration

Other health conditions supported by alpha-carotene

Products containing alpha-carotene