Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Rubia cordifolia (commonly known as Manjistha or Indian Madder) has a long history of use in traditional Ayurvedic and Unani medicine. It is primarily valued for its purported blood-purifying properties and its ability to support the lymphatic system, which includes lymph nodes and glands. The rationale in traditional systems is that Rubia cordifolia helps to remove toxins from the blood and lymph, thus assisting in the reduction of swelling or enlargement of lymph nodes (lymphadenopathy) that is believed to result from toxin buildup or "ama" (impurities) in the body. Ayurvedic texts such as the Charaka Samhita mention Manjistha as a remedy for conditions involving inflammation, glandular swellings, and skin disorders, often linked to underlying lymphatic congestion. Traditional practitioners may recommend it in formulations for swollen glands or as an adjunct in therapies aimed at detoxification.

However, direct scientific studies validating the efficacy of Rubia cordifolia specifically for swollen lymph nodes or glands are limited. Some laboratory research points to its anti-inflammatory, immunomodulatory, and antioxidant properties, which could theoretically support lymphatic health, but these effects have not been robustly studied in clinical settings for this indication. Therefore, while its use for lymphatic or glandular support is rooted in tradition and historical practice, current scientific evidence for this specific use is weak, justifying a modest evidence rating.

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