Deer Root, also known as Osmorhiza longistylis or wild sarsaparilla, has a history of use in North American indigenous herbal medicine. Traditionally, it has been used as a remedy for a variety of ailments, including as a “blood purifier” and to support the lymphatic system, particularly in cases of swollen lymph nodes or glands. The roots were often prepared as teas or poultices for their purported ability to reduce swelling and support the body's detoxification processes. However, scientific studies validating these uses are extremely limited or non-existent. There is a lack of clinical trials or pharmacological research specifically examining the effects of Deer Root on lymphatic function or on swollen glands in humans or animals. Most evidence supporting its use for this purpose is anecdotal, stemming from traditional herbal practices rather than controlled research. Therefore, while historical use suggests a role in addressing swollen lymph nodes, the overall evidence is weak, with no robust scientific validation to confirm efficacy or safety for this specific indication.