Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Omega-3 fatty acids, primarily found in fish oil, have been investigated as a supportive therapy in systemic lupus erythematosus (SLE, or lupus) due to their anti-inflammatory properties. Several small clinical trials and animal studies suggest that omega-3 supplementation may help reduce disease activity and improve certain symptoms in lupus patients. For example, randomized controlled trials (RCTs) have demonstrated modest improvements in disease activity scores, endothelial function, and inflammatory markers in SLE patients who received omega-3 supplements compared to placebo. These effects are thought to be mediated by the ability of omega-3 fatty acids (like EPA and DHA) to modulate immune responses, decrease production of pro-inflammatory cytokines, and potentially reduce oxidative stress.

However, the overall quality and quantity of evidence is limited. Most studies are small, of short duration, and vary in terms of dosages and formulations used. Meta-analyses and systematic reviews conclude that while there may be potential benefits, the evidence is not strong enough to recommend omega-3 fatty acids as a primary treatment for lupus. They are considered generally safe as an adjunct to standard therapy, with few reported side effects. In summary, there is some scientific basis for the use of omega-3 fatty acids in supporting lupus management, but the evidence is modest and further large-scale studies are needed.

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Other ingredients used for Lupus

Other health conditions supported by omega-3 fatty acids

Products containing omega-3 fatty acids

Nature's Sunshine Flax Seed Oil (With Lignans)