Evidence supporting the use of: Vitamin E
For the health condition: Liver Detoxification

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin E has been investigated for its potential role in supporting liver health, particularly in the context of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). Vitamin E is a potent lipid-soluble antioxidant, and oxidative stress is believed to play a key role in the pathogenesis of various liver diseases, especially NAFLD. Several clinical trials, including the prominent PIVENS trial, have demonstrated that vitamin E supplementation (typically at a dose of 800 IU/day) can improve liver histology, decrease liver enzymes, and reduce inflammation in non-diabetic adults with NASH. These findings have led some clinical guidelines (such as those from the American Association for the Study of Liver Diseases) to cautiously recommend vitamin E for select patients with biopsy-proven NASH. However, evidence is less robust for other liver conditions, and vitamin E is not considered a general "liver detox" agent. The use of vitamin E is not rooted in traditional herbal or folk medicine for liver health, but rather in modern scientific research on antioxidants and liver pathology. Potential risks, including increased all-cause mortality at high doses and possible increased risk of prostate cancer in men, mean that supplementation should be considered carefully and under medical supervision. Overall, while vitamin E shows promise for specific liver conditions associated with oxidative stress, the evidence is moderate and not universally applicable to all liver detoxification needs.

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Other ingredients used for Liver Detoxification

alfalfa
aloe vera
alpha-ketoglutarate (AKG)
amino acids
green chiretta
anthocyanins
apple
apricot
arjun tree
artichoke
asparagus
astragalus
barberry
barley
beet
myrobalan
berberine
beta caryophyllene
betel
black cumin
black garlic
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Indian frankincense
bovine liver
branched-chain amino acids
bupleurum falcatum
burdock
catalase
caterpillar mushroom
chaga mushroom
chicory
Chinese salvia root
chlorella
chokeberry
cinnamon
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cordyceps
cucumber
turmeric
curcumin
cuspidatum root
d-glucarate
dandelion
diallyl disulfide (DADS)
epigallocatechin gallate (EGCG)
gardenia
gentian root
ginger
gooseberry
green tea
hibiscus
Indian gum arabic tree
indole-3-carbinol
honeysuckle
knotweed
jujube
kale
kudzu
l-cysteine
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l-methionine
l-ornithine
lentinula edodes mycelia
licorice root
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lophatherum leaf
lovage
milk thistle
moringa
naringin
nettle
niacinamide (vitamin B3)
oleanolic acid
orange
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phosphatidylcholine
phospholipids
pollen
pumpkin
quercetin
redcurrant
reishi mushroom
rhubarb root
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
selenium
silymarin
spirulina
vegetable and fruit blend (proprietary)
vitamin B6
vitamin C
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seaweed
wasabia japonica
watercress
watermelon
wheat grass
whey protein
mulberry
zinc
sarsaparilla
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typhonium
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