Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Cholic acid is a primary bile acid that plays a significant role in the digestion and absorption of fats and fat-soluble vitamins in the intestine. Therapeutically, cholic acid is FDA-approved for use in certain rare inherited bile acid synthesis disorders, such as bile acid synthesis disorders due to single enzyme defects and peroxisomal disorders. In these specific cases, supplementation with cholic acid can improve bile flow and reduce the accumulation of toxic bile acid intermediates, thereby supporting liver function and preventing progressive liver damage.

However, the use of cholic acid or "cholic acids (unspecified)" for general liver detoxification in healthy individuals or those with common liver diseases is not supported by robust clinical evidence. There are no well-conducted clinical trials proving its efficacy for general detoxification or as a broad treatment for liver diseases outside of the rare genetic disorders mentioned. The rationale for its use in detoxification often stems from its physiological role in bile formation and the excretion of waste products, but this does not directly translate to therapeutic benefit for the general population.

In summary, cholic acid has a scientifically validated, but very specific, role in inherited liver disorders related to bile acid metabolism. Its use for generic liver detoxification is not broadly supported by scientific evidence, and the evidence rating for this indication is therefore moderate (3/5), reflecting its proven benefit in rare disease contexts but not for general detoxification.

More about Cholic acids (unspecified)
More about Liver Detoxification

Other ingredients used for Liver Detoxification

alfalfa
aloe vera
alpha-ketoglutarate (AKG)
amino acids
green chiretta
anthocyanins
apple
apricot
arjun tree
artichoke
asparagus
astragalus
barberry
barley
beet
myrobalan
berberine
beta caryophyllene
betel
black cumin
black garlic
radish
Indian frankincense
bovine liver
branched-chain amino acids
bupleurum falcatum
burdock
catalase
caterpillar mushroom
chaga mushroom
chicory
Chinese salvia root
chlorella
chokeberry
cinnamon
Coptis chinensis
cordyceps
cucumber
turmeric
curcumin
cuspidatum root
d-glucarate
dandelion
diallyl disulfide (DADS)
epigallocatechin gallate (EGCG)
gardenia
gentian root
ginger
gooseberry
green tea
hibiscus
Indian gum arabic tree
indole-3-carbinol
honeysuckle
knotweed
jujube
kale
kudzu
l-cysteine
l-glutathione
l-methionine
l-ornithine
lentinula edodes mycelia
licorice root
liquid liver fractions
lophatherum leaf
lovage
milk thistle
moringa
naringin
nettle
niacinamide (vitamin B3)
oleanolic acid
orange
perilla
phosphatidylcholine
phospholipids
pollen
pumpkin
quercetin
redcurrant
reishi mushroom
rhubarb root
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
selenium
silymarin
spirulina
vegetable and fruit blend (proprietary)
vitamin B6
vitamin C
vitamin E
seaweed
wasabia japonica
watercress
watermelon
wheat grass
whey protein
mulberry
zinc
sarsaparilla
cascara sagrada
typhonium
neem tree
enicostemma littorale
clerodendrum indicum
smilax
tinospora cordifolia
fumaria parviflora
picrorhiza kurroa
rubia cordifolia
swertia
lingzhi
lingusticum wallichii
goldenrod
bile salt
morus
myrrh
root tuber
chrysanthemum
ganoderma
lotus seed
birch
couch grass
sheep's sorrel
anemarrhena asphodeloides
purslane
coix
polyporus
gentiana macrophylla
cleavers
noni
biota seed
goji berry
algae
ashitaba
soursop
Arjuna
akebia
Ankaflavin
Anthraquinone
Ardisia
Agrimony
Apigenin
Antrodia camphorata
Achyranthes
Anamu
Albizia
AHCC
Aucubin
Andrographolide
Avocado
Albumin
American Liverleaf
Appleblossom Cassia
Asam gelugor
Alpha-Lipoic Acid
Astragaloside
Andrographis
Adzuki bean
Alsonia scholaris
Agrimonia pilosa
Allyl Sulfide
Alisma
Allium tuberosum
Amor seco
Arjunolic acid
Astragalin
Atractylone
Black Seed
Baikal Skullcap
Blue Flag
Borotutu
Blackthorn
bergenin
Blepharis
Balsam
Brassica
Belleric myrobalan
Beef liver
Barleria
Berberis (unspecified)
Baicalein
Bael
Butternut
Basidiomycota
boldo
Black Gram
Baccharoides anthelmintica
Banyan
Black Nightshade
Bitter principals
Bacteria
Black root
Bifidobacteria
BCAA
Bupleurum
benzyl isothiocyanate
Bassia scoparia
Bergenia
Bignay
Bottle gourd
Centaury
Chinese Silkvine
cholic acid
Carqueja
Chebulic acid
Coriolus mushroom
Coriander
Clerodendrum phlomidis
Centaurium erythraea
Cyathula
Chinese Fleeceflower
Cynarin
Chinese Pond Turtle
Cruciferous
Centella asiatica
Capers
Chanca Piedra
Celandine
Cinnamic Acid
Chinese Ligustrum berry
Copalchi
Corktree
C-Phycocyanin
Cabbage
Chirata
Calamus
Chebulinic acid
Corilagin
Coumaric acid
Cynaropicrin
Cynodon dactylon
Carthamus
Clerodendrum indicum
Diallyl sulfide
Dihydromyricetin
DL-Methionine
Deoxyandrographolides
Dithiolthiones
Desmodium
Duckweed
Ellagic Acid
Erodium cicutarium
Emblicanin
Endive
Embelia
Ellagitannin
Emodin
Fucoidan
Flueggea suffruticosa
Fumitory
Fo-Ti
Ficus religiosa
Flavanones
Ficus simplicissima
Flavans
Flavonones
Flavonolignan
Gallic Acid
Genipap
Gamma-Glutamylcysteine
Gallate
Glycophospholipid
Glycosaponin
Glutathione
Glycine
Garden Cress
Gardenia jasminoides
Glucoraphanin
Glycyrrhizin
Golden Shower Tree
Glucuronic acid
Glucaric acid
Little ironweed
Prickly Pear Cactus
Rhubarb
walnut

Other health conditions supported by Cholic acids (unspecified)

Gall Bladder (sluggish or removed)
Gall Stones
Jaundice (adults)
Liver Detoxification

Products containing Cholic acids (unspecified)

We currently have no products on Caring Sunshine that contain this ingredient.