Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Chinese Ligustrum berry, known as Ligustrum lucidum or "Nu Zhen Zi," has a long history of use in Traditional Chinese Medicine (TCM). It is primarily used to support liver and kidney health, often as a tonic to nourish the "yin" and improve vitality, especially in cases of weakness, dizziness, and tinnitus. The rationale for its use in "liver detoxification" is based on TCM theory, which conceptualizes the liver as a central organ in maintaining bodily harmony and processing toxins, although these ideas do not map directly onto modern biomedical understandings of liver function or detoxification.

Modern scientific evidence for Ligustrum lucidum’s effects on liver detoxification is limited. Some preclinical studies suggest that certain compounds in Ligustrum lucidum, such as oleanolic acid and other triterpenoids, may have hepatoprotective effects, including antioxidant properties and the potential to reduce chemically-induced liver injury in animal models. However, robust clinical studies in humans supporting its use specifically for liver detoxification are lacking. Therefore, the use of Chinese Ligustrum berry for liver detoxification is justified primarily by tradition, with only weak scientific support from early-stage laboratory studies but insufficient evidence from clinical trials.

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