Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bile salts are primarily used in medical practice to support digestion, particularly in cases of bile acid insufficiency due to gallbladder removal or certain liver diseases, rather than directly for "liver detoxification." Scientifically, the liver's detoxification processes (phase I and II metabolism) do not directly require supplemental bile salts; instead, these processes rely on hepatic enzymes and cofactors. However, bile salts do play an indirect role by facilitating the excretion of certain metabolites and toxins in bile, which is then eliminated via the gastrointestinal tract. Some practitioners and supplement manufacturers claim that bile salt supplements can support "liver detox," but there is limited direct evidence in human studies to substantiate these claims. Most clinical research focuses on their use in treating cholestatic liver diseases or aiding digestion after cholecystectomy, not on enhancing liver detoxification itself. Therefore, while bile salts are important for bile flow and toxin elimination via the intestines, the scientific evidence supporting their use specifically for liver detoxification is weak, with a lack of robust human clinical trials. The rating of 2 reflects a theoretical basis and some indirect support, but not strong direct scientific validation.

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Products containing bile salt

Nature's Sunshine Bowel Detox
Nature's Sunshine Dieter's Cleanse
Nature's Sunshine Food Enzymes