Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bifidobacteria is a genus of probiotic bacteria that has been studied for a variety of health benefits, primarily related to gut health. Its use in supporting or treating liver detoxification is based on emerging scientific evidence, though the overall quality and quantity of research is still limited. Preclinical studies and some small-scale clinical trials suggest that Bifidobacteria may play a role in modulating the gut–liver axis. Dysbiosis, or an imbalance in gut microbiota, has been linked to liver diseases such as non-alcoholic fatty liver disease (NAFLD) and hepatic encephalopathy. Some interventions using Bifidobacteria-containing probiotics have shown reductions in markers of liver inflammation and improvements in liver function tests, likely due to decreased intestinal permeability, reduction of endotoxemia, and modulation of immune responses. However, most studies use multi-strain probiotics rather than Bifidobacteria alone, and often in combination with lifestyle or dietary changes, making it difficult to isolate the specific effects of Bifidobacteria. While early results are promising and provide a mechanistic rationale, robust, large-scale human clinical trials are still lacking. Therefore, the use of Bifidobacteria for liver detoxification has some scientific basis but cannot yet be considered a fully validated or standard approach.

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