Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Hydroxyproline is an amino acid found predominantly in collagen, which is a major structural protein in connective tissues such as ligaments, tendons, and skin. Its presence is essential for the stability and function of collagen fibers. The rationale for using hydroxyproline supplements (often in the form of collagen hydrolysates) to support ligament healing comes from the understanding that injured ligaments require new collagen synthesis during the repair process, and hydroxyproline is a marker of collagen content.

Scientific studies have shown that oral collagen supplementation can increase circulating levels of hydroxyproline. Some animal and in vitro studies suggest that collagen peptides or hydroxyproline may enhance collagen synthesis and stimulate the repair of connective tissue. However, direct clinical evidence in humans specifically targeting ligament injuries is limited. A few small studies and reviews suggest potential benefits for joint health and tendon repair, but the evidence for ligament healing is sparse and largely extrapolated from basic science or studies on related tissues like tendons and skin.

In summary, while there is a plausible biochemical rationale and some preclinical support for hydroxyproline supplementation in supporting ligament repair, high-quality human clinical trials are lacking. The current evidence is rated as 2 (weak to moderate), reflecting promising but not definitive scientific support.

More about hydroxyproline
More about Ligaments (torn or injured)

Other ingredients used for Ligaments (torn or injured)

bovine gelatin
collagen
turmeric
gelatin
l-proline
vitamin C
solomon's seal
arnica
Drynaria

Other health conditions supported by hydroxyproline

Cartilage Damage
Ligaments (torn or injured)
Surgery (healing from)
Wounds and Sores

Products containing hydroxyproline

We currently have no products on Caring Sunshine that contain this ingredient.