Evidence supporting the use of: Reishi mushroom
For the health condition: Leukemia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Reishi mushroom (Ganoderma lucidum) has a long history of use in traditional Chinese medicine, where it is prized for its supposed immune-boosting and health-promoting properties. In the context of leukemia, there is some scientific interest in reishi due to its bioactive compounds, such as polysaccharides and triterpenoids, which have demonstrated immunomodulatory and potential anti-cancer effects in laboratory studies. In vitro experiments suggest that extracts from reishi may induce apoptosis (programmed cell death) in certain leukemia cell lines and may inhibit their proliferation. Additionally, some animal studies have shown that reishi extracts can modulate immune responses and potentially enhance the efficacy of chemotherapy drugs.

However, clinical evidence supporting the use of reishi mushroom specifically for leukemia in humans is limited and of low quality. Most human studies are small, preliminary, or focused on general immune function or quality of life rather than direct anti-leukemic effects. Comprehensive clinical trials are lacking, and there are no established guidelines recommending reishi as a treatment for leukemia. Therefore, while there is a scientific rationale and some laboratory evidence, the current level of evidence is weak (rated 2 out of 5), and reishi should not be considered a substitute for conventional leukemia therapies. Patients interested in using reishi should consult their healthcare provider.

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