Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Stillingia, commonly known as Queen's root or Stillingia sylvatica, has a history of traditional use in North American herbal medicine, particularly among Native American groups and 19th-century eclectic physicians. It was often used for its purported "blood-purifying" properties and as a remedy for various skin diseases and lesions, including ulcers, boils, and chronic skin eruptions. The root was typically prepared as a decoction or tincture and applied both internally and externally to address skin lesions. Historical herbal texts, such as King's American Dispensatory (1898), document its use in treating cutaneous disorders and syphilitic lesions, attributing effects primarily to its acrid, stimulating, and purportedly alterative actions.

However, the scientific evidence supporting stillingia’s efficacy for lesions is extremely limited. Modern clinical studies are lacking, and the pharmacological mechanisms remain poorly defined. Some in vitro studies indicate the plant contains saponins and diterpenes that may have irritant or mild anti-inflammatory properties, but these findings are preliminary and do not specifically validate its use for skin lesions in humans. Thus, the continued use of stillingia for lesions is grounded in tradition rather than robust scientific validation, and safety concerns due to its irritant properties have further limited its contemporary use.

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