Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Babchi (Psoralea corylifolia) has a long history of use in traditional Ayurvedic and Chinese medicine for the management of skin diseases, including leprosy (Hansen's disease). Ancient texts such as the Charaka Samhita and Sushruta Samhita mention Babchi seeds as part of remedies for various skin conditions, including those presenting with skin discoloration, depigmentation, and ulcers, which are symptoms associated with leprosy. The seeds were often used in the form of pastes or decoctions applied directly to affected areas.

The traditional rationale for Babchi's use lies in its properties as a 'kushtaghna' (disease-removing) herb, believed to improve skin health and promote repigmentation. Some of its main phytochemicals, such as psoralen, have photosensitizing effects, which are thought to stimulate skin cell turnover and melanogenesis. In historical practice, Babchi was sometimes used alongside exposure to sunlight.

Modern scientific evidence for its efficacy in treating leprosy specifically is limited. While a few studies have investigated the antimicrobial and immunomodulatory properties of Babchi extracts, there is insufficient clinical trial data to confirm its effectiveness against Mycobacterium leprae, the causative agent of leprosy. Most available studies focus on Babchi’s benefits in vitiligo and other dermatological disorders rather than leprosy. Therefore, its use for leprosy remains primarily justified by traditional knowledge rather than robust scientific validation.

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