Evidence supporting the use of: Slippery Elm
For the health condition: Leaky Gut Syndrome

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Slippery Elm (Ulmus rubra) has a long history of traditional use in North American herbal medicine, especially among Indigenous peoples, for soothing the digestive tract. Its inner bark contains mucilage, a gel-like substance that becomes slippery when mixed with water. Traditionally, Slippery Elm has been used to help with sore throats, coughs, and various digestive complaints, including symptoms associated with what is now termed "leaky gut syndrome"—such as diarrhea, constipation, and general gut inflammation. The mucilage is believed to coat the lining of the stomach and intestines, providing a protective barrier and soothing irritation. However, there is a lack of robust scientific research specifically investigating Slippery Elm’s effects on intestinal permeability (“leaky gut”) in humans. While in vitro and animal studies suggest that mucilaginous herbs may have soothing and anti-inflammatory properties, direct evidence for Slippery Elm’s efficacy in treating or supporting leaky gut syndrome in humans is minimal. Most clinical studies focus on its use in conditions like irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD), sometimes finding symptomatic relief but not changes in gut permeability. In summary, the use of Slippery Elm for leaky gut syndrome is primarily based on traditional usage and plausible mechanisms rather than strong scientific validation. Its safety profile is generally good, but its efficacy for this specific condition remains unproven and rated as low (2/5) due to insufficient clinical evidence.

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