Evidence supporting the use of: Slippery Elm
For the health condition: Leaky Gut Syndrome
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Slippery Elm (Ulmus rubra) has a long history of traditional use in North American herbal medicine, especially among Indigenous peoples, for soothing the digestive tract. Its inner bark contains mucilage, a gel-like substance that becomes slippery when mixed with water. Traditionally, Slippery Elm has been used to help with sore throats, coughs, and various digestive complaints, including symptoms associated with what is now termed "leaky gut syndrome"—such as diarrhea, constipation, and general gut inflammation. The mucilage is believed to coat the lining of the stomach and intestines, providing a protective barrier and soothing irritation. However, there is a lack of robust scientific research specifically investigating Slippery Elm’s effects on intestinal permeability (“leaky gut”) in humans. While in vitro and animal studies suggest that mucilaginous herbs may have soothing and anti-inflammatory properties, direct evidence for Slippery Elm’s efficacy in treating or supporting leaky gut syndrome in humans is minimal. Most clinical studies focus on its use in conditions like irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD), sometimes finding symptomatic relief but not changes in gut permeability. In summary, the use of Slippery Elm for leaky gut syndrome is primarily based on traditional usage and plausible mechanisms rather than strong scientific validation. Its safety profile is generally good, but its efficacy for this specific condition remains unproven and rated as low (2/5) due to insufficient clinical evidence.
Other ingredients used for Leaky Gut Syndrome
2'-Fucosyllactoseakkermansia muciniphila
aloe vera
bacillus coagulans
bacillus subtilis
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
butyrate triglyceride
chamomile
colostrum
turmeric
dandelion
fructooligosaccharides (FOS)
immunoglobin G
inulin
l-glutamine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus casei
lactobacillus fermentum
lactobacillus gasseri
lactobacillus helveticus
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
licorice root
marshmallow
potato starch
butyric acid
psyllium
saccharomyces boulardii
slippery elm bark
tributyrin
vitamin D
xylooligosaccharides
zinc
Acemannan
Bifidobacterium
Bifidobacterium adolescentis
Bifidobacterium animalis
Bacteria
Bifidobacteria
Bacillus
Other health conditions supported by Slippery Elm
Abdominal PainAcid Indigestion
Anal Fistula or Fissure
Appetite (deficient)
Bronchitis
Burns and Scalds
Canker Sores
Colitis
Constipation (adults)
Constipation (children)
Cuts
Diarrhea
Digestion (poor)
Diverticulitis
Duodenal Ulcers
Dyspepsia
Eczema
Emphysema
Enteritis
Gas and Bloating
Gastritis
Gingivitis
Glands (swollen lymph)
Indigestion
Inflammation
Inflammatory Bowel Disorders
Injuries
Irritable Bowel Syndrome
Itching
Itching (rectal)
Laryngitis
Leaky Gut Syndrome
Leucorrhea
Pain (general remedies for)
Psoriasis