Evidence supporting the use of: Inulin
For the health condition: Leaky Gut Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Inulin is a type of prebiotic fiber naturally found in chicory root, onions, garlic, and other plants. Its use in supporting "Leaky Gut Syndrome" is primarily based on its ability to nourish beneficial gut bacteria, which in turn may help maintain or restore intestinal barrier function. Scientific studies have shown that inulin can increase populations of Bifidobacteria and Lactobacilli in the gut, which are associated with improved gut health and reduced inflammation. Some animal studies and limited human research indicate that inulin may enhance the production of short-chain fatty acids (especially butyrate), which are known to support the integrity of the intestinal lining. This could, theoretically, help prevent or repair increased intestinal permeability—a hallmark of "leaky gut." However, "Leaky Gut Syndrome" is not broadly recognized as a formal medical diagnosis, and high-quality clinical trials specifically investigating inulin’s effect on intestinal permeability in humans are limited. Most evidence comes from mechanistic studies or those on related gastrointestinal conditions. Thus, while there is some scientific basis for inulin’s potential benefits for gut barrier function, the direct evidence supporting its use in "leaky gut" is still emerging and not robust. Overall, inulin is a plausible adjunct for gut health, but its efficacy for Leaky Gut Syndrome specifically requires further validation in well-designed human studies.

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