Fruit & Vegetable Blends are commonly used to support the large intestine (colon) due to their high content of dietary fiber, polyphenols, vitamins, and other phytonutrients. Scientific evidence suggests that diets rich in fruits and vegetables are associated with improved colon health. Fiber, particularly insoluble fiber found in many fruits and vegetables, adds bulk to stool and promotes regular bowel movements, reducing the risk of constipation—a common colon complaint. Soluble fibers are fermented in the colon, producing short-chain fatty acids (SCFAs) such as butyrate, which have anti-inflammatory and protective effects on colon cells.

Multiple epidemiological studies have linked higher fruit and vegetable intake to a lower risk of colorectal cancer and other disorders of the large intestine. Polyphenols and antioxidants found in these foods may also modulate gut microbiota composition, supporting a healthy colonic environment.

While most of the evidence comes from studies on whole foods rather than processed blends, some research suggests that powdered or concentrated blends can provide similar, though possibly less potent, benefits if they retain fiber and bioactive compounds. However, not all commercial blends contain sufficient fiber to have the same effect as whole fruits and vegetables, so efficacy depends on the specific product's composition.

In summary, there is moderate scientific evidence that fruit and vegetable blends can support colon health, primarily due to their fiber and phytonutrient content, although whole food intake is generally more strongly supported.