Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Docusate calcium is a stool softener that is scientifically validated for use in supporting the large intestines (colon) by facilitating easier passage of stool. It acts as a surfactant, reducing the surface tension of stool, allowing water and fats to penetrate and soften the fecal mass. This mechanism promotes bowel movements and helps relieve constipation, particularly in patients who should avoid straining (such as those recovering from surgery or childbirth, or with certain heart conditions). Numerous clinical studies and systematic reviews have established the effectiveness of docusate salts (including docusate calcium and docusate sodium) in softening stool and alleviating mild to moderate constipation, although some meta-analyses suggest that its efficacy may be modest compared to other laxatives. Nevertheless, it remains widely recommended in clinical practice guidelines for short-term relief of constipation. Docusate calcium is not absorbed systemically and works locally in the colon, which is why it is specifically used to support the function of the large intestine. There is no significant traditional or herbal use for docusate calcium; its application is rooted entirely in modern pharmaceutical science.

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