Bifidobacterium longum is a probiotic bacterium commonly found in the human gastrointestinal tract, especially in the colon. Its use to support large intestine (colon) health is supported by scientific evidence.

Multiple clinical studies and reviews indicate that B. longum supplementation can help maintain and restore healthy gut flora, which is crucial for colon health. It has been shown to enhance the gut barrier, outcompete pathogenic bacteria, and modulate immune responses in the intestinal mucosa. Research suggests that B. longum may alleviate symptoms of irritable bowel syndrome (IBS), reduce inflammation in patients with inflammatory bowel diseases such as ulcerative colitis, and improve stool regularity.

For example, a 2016 review in the journal Beneficial Microbes summarized clinical trials showing that B. longum can reduce abdominal discomfort and bloating, and improve bowel habits. Another randomized controlled trial published in Alimentary Pharmacology & Therapeutics found that supplementation with B. longum reduced symptoms in IBS patients compared to placebo. While not all studies show strong effects and more research is needed to define optimal strains and dosages, the current body of evidence supports its beneficial role in colon health.

Thus, B. longum is scientifically validated as a means of supporting large intestine function, particularly in relation to gut microbial balance and gut barrier protection.