Asian Plantain (Plantago asiatica), also known as Che Qian Zi in Traditional Chinese Medicine (TCM), has a long history of use as a remedy for various conditions affecting the Large Intestine (Colon) and urinary system. In TCM, Asian Plantain seeds are believed to "clear heat" and "drain dampness," which conceptually includes addressing diarrhea, dysentery, and other gastrointestinal disturbances. Its mucilaginous seeds are thought to help soothe the intestinal lining and promote healthy bowel movements, and it is often included in herbal formulas for issues such as loose stools or diarrhea.

However, rigorous scientific evidence supporting its benefit specifically for the large intestine in humans is limited. Some laboratory and animal studies indicate that Plantago species possess anti-inflammatory, antioxidant, and mild laxative properties, which could theoretically benefit colon health. The mucilage from the seeds may help bulk stools and support bowel regularity, similar to the better-studied Plantago ovata (psyllium). Despite these findings, there is a lack of robust clinical trials directly demonstrating its efficacy for colon support in humans. Thus, its use for the large intestine is justified primarily by traditional practice rather than strong scientific validation.