Synopsis

Source of validity: Traditional
Rating (out of 5): 4

Anthraquinone compounds, particularly those found in plants such as senna, cascara sagrada, and aloe, have a long history of traditional use to support the large intestine (colon) as stimulant laxatives. These compounds work by irritating the colon wall, stimulating peristalsis, and increasing water and electrolyte secretion in the bowel, which helps relieve constipation. Historical records show that preparations containing anthraquinone glycosides were used in ancient Egypt and were common in traditional European and Asian medicine for bowel regulation. Although these uses are well established in herbal medicine traditions, modern scientific validation is moderate—while the laxative effect is well documented pharmacologically, there are concerns over long-term safety, including the risk of dependency and potential for adverse effects such as electrolyte imbalance or melanosis coli. Regulatory agencies in some countries have restricted or advised caution in the use of anthraquinone-containing laxatives. Nevertheless, the traditional evidence for supporting colon function, specifically as a short-term remedy for constipation, is strong and supported by pharmacological mechanisms, but long-term or routine use is not recommended without medical supervision.

More about Anthraquinone
More about Large Intestines (Colon)

Other ingredients that support Large Intestines (Colon)

Other body systems supported by Anthraquinone

Products containing Anthraquinone