Evidence supporting the use of: Lactobacillus casei
For the health condition: Lactose Intolerance

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lactobacillus casei is a probiotic bacterium that has been investigated for its potential to support individuals with lactose intolerance. The scientific rationale behind its use centers on its ability to produce the enzyme beta-galactosidase (also known as lactase), which breaks down lactose into glucose and galactose, thereby aiding in lactose digestion.

Several clinical studies and reviews have evaluated the effects of L. casei and other probiotic strains on lactose digestion. While the evidence is not as robust or consistent as that for Lactobacillus acidophilus or Bifidobacterium species, some studies indicate that supplementation with L. casei may reduce symptoms such as bloating, diarrhea, and abdominal pain in lactose-intolerant individuals. A 2015 systematic review published in Nutrition Journal concluded that specific probiotic strains, including L. casei, can modestly improve lactose digestion and tolerance, though effects vary based on dosage, strain, and duration of use.

Overall, the scientific evidence supporting L. casei for lactose intolerance is moderate (rated 3/5), with some positive clinical outcomes but variability in results and a need for further well-controlled studies. The use of L. casei is justified primarily by its scientifically demonstrated enzymatic activity and published clinical data, rather than by historical or traditional use.

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