Evidence supporting the use of: Lactobacillus acidophilus
For the health condition: Lactose Intolerance

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lactobacillus acidophilus is a probiotic bacterium commonly used to support individuals with lactose intolerance. The scientific rationale behind its use is based on its ability to produce the enzyme beta-galactosidase (lactase), which helps break down lactose into glucose and galactose, making it easier for lactose-intolerant individuals to digest dairy products. Several clinical studies and meta-analyses have explored the efficacy of L. acidophilus in reducing symptoms of lactose intolerance, such as bloating, cramping, and diarrhea.

Research indicates that consuming yogurt or fermented milk products containing live cultures of L. acidophilus can improve lactose digestion and alleviate symptoms in some lactose-intolerant individuals. For example, a review published in the American Journal of Clinical Nutrition (1995) and a meta-analysis in Nutrition Reviews (2015) found moderate evidence that probiotics, especially L. acidophilus, can reduce lactose maldigestion symptoms. The benefits are thought to occur because live probiotic bacteria continue to produce lactase as they transit through the gut.

However, the magnitude of benefit varies between individuals, and not all studies have found significant improvements. The overall evidence is moderate, supporting a rating of 3 out of 5. L. acidophilus is thus justified for use based on scientific evidence, though it should not be considered a complete substitute for lactase enzyme supplements or strict dietary lactose restriction in highly sensitive individuals.

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