Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bifidobacterium adolescentis is a probiotic bacterium that has been studied for its potential role in alleviating symptoms of lactose intolerance. The rationale for its use is grounded in its ability to produce the enzyme β-galactosidase (lactase), which hydrolyzes lactose into glucose and galactose—sugars that can be absorbed by the human intestine. Several in vitro and animal studies have demonstrated that B. adolescentis strains can survive gastrointestinal transit and exhibit significant lactase activity. Some small-scale human trials and ex vivo studies suggest that supplementation with certain Bifidobacterium strains, including B. adolescentis, may improve lactose digestion and reduce symptoms such as bloating and diarrhea in lactose-intolerant individuals.

However, most clinical studies on probiotics for lactose intolerance have focused on mixed strains or other Bifidobacterium species (such as B. longum and B. animalis). The direct evidence regarding B. adolescentis is more limited, although mechanistically plausible and supported by its enzymatic capability. Overall, there is moderate scientific support for the use of B. adolescentis in managing lactose intolerance, but larger, well-controlled clinical trials are needed to fully establish efficacy and optimal dosing.

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