Evidence supporting the use of: Vitamin D3
For the body system: Kidneys

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin D3 (cholecalciferol) plays a crucial role in kidney health, with its use supported by significant scientific evidence. The kidneys are responsible for converting inactive vitamin D into its active form, calcitriol, which is essential for calcium and phosphate regulation in the body. In chronic kidney disease (CKD), this conversion is impaired, often leading to vitamin D deficiency, disturbances in mineral metabolism, and bone disorders such as renal osteodystrophy. Numerous clinical guidelines, including those from the Kidney Disease: Improving Global Outcomes (KDIGO) organization, recommend supplementation with vitamin D3 or its analogs in patients with CKD to manage secondary hyperparathyroidism and bone mineral disorders.

Several randomized controlled trials and meta-analyses have demonstrated that vitamin D3 supplementation in patients with CKD can reduce parathyroid hormone (PTH) levels, improve bone health, and may have beneficial effects on cardiovascular risk factors. However, routine use in individuals with normal kidney function for direct "kidney support" is not established. The main indications remain prevention and treatment of vitamin D deficiency and management of complications arising from impaired kidney function.

In summary, the use of vitamin D3 to support the kidneys is scientifically validated, especially in the context of kidney disease, where it addresses specific metabolic disturbances. Its role in general kidney health beyond these indications is still under investigation.

More about vitamin D3
More about Kidneys

Other ingredients that support Kidneys

alfalfa
amino acids
anthocyanins
asparagus
astragalus
bamboo
basil
bearberry
black cumin
black garlic
radish
sesame
bovine
bovine kidney
broccoli
burdock
caterpillar mushroom
celery
chicory
cordyceps
dandelion
melon
fruit blend (proprietary)
fu ling
garlic bulb
gokhru
gooseberry
grape
green tea
greens blend (proprietary)
hibiscus
horseradish
horsetail
l-glutathione
lemon
lophatherum leaf
lovage
mannitol
marshmallow
methenamine
moringa
nettle
oleanolic acid
parsley
pear
phellodendron amurense
plantain
potassium
pumpkin
rehmannia glutinosa
rhizome
rhubarb root
scrophularia root
stevia
tribulus
vegetable blend (proprietary)
vitamin B
vitamin D
vitamin D3
seaweed
water
watercress
watermelon
mulberry
sarsaparilla
jiaogulan
punarnava
smilax
rubia cordifolia
swertia
chaff flower
lingzhi
goldenrod
yarrow
morus
lemongrass
sodium salt
root tuber
juniper berries
solomon's seal
cistanche
dodder
eucommia
ganoderma
lotus seed
morinda
electrolytes blend (proprietary)
cornsilk
buchu
birch
couch grass
sheep's sorrel
queen of the meadow
anemarrhena asphodeloides
hydrangea
purslane
coix
polyporus
cleavers
noni
millet seed
herbal blend (proprietary)
AMP-activated protein kinase (AMPK)
ashitaba
gravel root
akebia
Antler
Anamarrhena
Angelica
Arbutin
Agrimony
Antrodia camphorata
Achyranthes
Alchornea
Aerva lanata
Astragaloside
Armillaria mellea
Adzuki bean
Agrimonia pilosa
Alisma
Anemarrhena
Abuta
Allium tuberosum
Amor seco
Black Seed
Baikal Skullcap
bergenin
Bicarbonate
Blepharis
Bishop's Weed
Barleria
Baicalein
Bean
Begonia fimbristipula
boldo
Black Gram
Bur-Reed
Ba Ji Tian
Bee products
Bombax
Borassus aethiopum
Baicalin
Bassia scoparia
Bergenia
Boerhavia diffusa
Bottle gourd
Curculigo orchicides
Cowpea
Chinese Mountain Ant
Carrapicho
Cucurbita
Catalpol
Clerodendrum phlomidis
Cynomorium
Cyathula
Chinese Fleeceflower
Cornflower
Chinese Pond Turtle
Common Thatching grass
Chanca Piedra
Coconut Water
Chinese Ligustrum berry
Corktree
Cranesbill
Cornus
Chiococca alba
Costus
Currant
Dianthus
Didymocarpus
Dendrobium
Deer Root
Deer Velvet
Drynaria
Dwarf Nettle
Dipsacus
Erigeron
Eupolyphaga sinensis
Erodium cicutarium
Eclipta
Euryale seed
Elk antler
Echinodorus
Elephant's Head
Eupatorium
Eucommia ulmoides
Emodin
Flavonoids
Garlic
Lotus
Lily
Mallow
Orchid
Rhubarb