Black Seed Oil, derived from Nigella sativa, has a long history of use in traditional medicine systems, particularly within Middle Eastern, South Asian, and North African cultures. Traditional practitioners have recommended Black Seed Oil for a variety of ailments, including those affecting the kidneys and urinary tract. It has often been used as a general tonic and for purported detoxification, which some traditional systems associate with supporting kidney health.

Scientific research on Black Seed Oil's direct effects on the kidneys is limited and inconclusive. A few animal studies suggest possible protective effects against chemically induced kidney damage, likely due to its antioxidant and anti-inflammatory properties, particularly attributed to thymoquinone, its primary active compound. For example, some studies in rats have indicated that Black Seed extract may reduce markers of kidney damage or improve kidney function under experimental conditions. However, these findings have not been reliably replicated in human clinical trials, and there is insufficient evidence to draw strong conclusions about its efficacy for kidney support in humans.

In summary, while Black Seed Oil is traditionally used to support kidney health, robust scientific validation is lacking, and its use for this purpose is based primarily on historical practices rather than modern clinical evidence.