Evidence supporting the use of: Akebia (unspecified)
For the health condition: Kidney Stones

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Akebia, particularly Akebia quinata and Akebia trifoliata, has a long history of use in traditional Chinese medicine (TCM) for promoting urination and alleviating conditions related to urinary tract obstruction, including kidney stones. The medicinal part, often referred to as “Mu Tong” in TCM, is traditionally employed as a diuretic and to “clear heat,” which is believed to help with the passage of stones or relieve symptoms associated with them. Ancient texts and materia medica describe its use in formulas for “stranguria” (painful urination), which can include symptoms of urinary stones. Modern scientific validation for Akebia’s efficacy in treating kidney stones is limited. Some in vitro and animal studies suggest that compounds found in Akebia may have mild diuretic effects and could help reduce urinary tract inflammation. However, robust clinical trials in humans specifically addressing kidney stone prevention, dissolution, or treatment are lacking. Safety concerns also exist: confusion between Akebia (Mu Tong) and Aristolochia species (known to be nephrotoxic) has led to regulatory concerns in some countries. In summary, the use of Akebia for kidney stones is primarily supported by traditional medical systems, with limited scientific evidence and no high-quality clinical trials confirming efficacy. Its use should be approached with caution, and it is not considered part of standard medical care for kidney stones in Western medicine.

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