Evidence supporting the use of: Sarsaparilla
For the body system: Joints
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Sarsaparilla (Smilax spp.) has a long history of use in traditional herbal medicine, especially in indigenous and folk practices, for supporting joint health and alleviating symptoms associated with rheumatism and arthritis. Historically, sarsaparilla was employed as a remedy for joint pain, swelling, and inflammation, often in the form of teas or tinctures. The rationale in traditional systems was based on observed symptomatic relief, not on a mechanistic understanding of disease or inflammation.
From a scientific standpoint, there is limited evidence supporting the efficacy of sarsaparilla for joint health. Some laboratory studies suggest that sarsaparilla contains compounds such as saponins and phytosterols, which may possess anti-inflammatory properties. However, these findings are preliminary and mostly based on in vitro or animal studies, not on rigorous clinical trials in humans with joint issues. No robust, large-scale human studies have confirmed a benefit for joint conditions such as arthritis.
In summary, while sarsaparilla is traditionally used to support the joints, scientific validation is minimal, and evidence is not strong. Its use in this context is best described as traditional, with a moderate degree of preliminary scientific plausibility but insufficient direct human evidence to warrant a higher rating.
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alfalfaalgal oil
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beta caryophyllene
black cumin
black currant
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borage oil
boron
Indian frankincense
bovine
bovine gelatin
broccoli
bromelain
burdock
cabbage leaf
calamari oil
cartilage
cat's claw
cherry
Chinese salvia root
chondroitin
cissus quadrangularis
collagen
turmeric
curcumin
cuspidatum root
devil's claw
dog rose
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fish oil
fish protein
flavonols
flaxseed
gamma linolenic acid (GLA)
gelatin
ginger
glucosamine
gokhru
gooseberry
gotu kola
green lipped mussel
guggul
horsetail
hyaluronic acid
Indian tinospora
knotweed
krill oil
l-proline
mackerel
manganese
marine lipid
methylsulfonylmethane (MSM)
microcrystalline hydroxyapatite concentrate (MCHC)
milk
moringa
mustard seed
n-acetyl-glucosamine
nettle
olive
omega-3 fatty acids
omega-6 fatty acids
phellodendron amurense
phytocannabinoids
pine bark
pineapple
plantain
protein
quercetin
rehmannia glutinosa
rhizome
rose hips
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
scrophularia root
serratiopeptidase
silicon
black ginger
specialized pro-resolving mediators (SPMs)
triphala
vitamin C
vitamin D
seaweed
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white willow
wild yam
sarsaparilla
red clover
boneset
chickweed
gastrodia
capsicum
clerodendrum indicum
hedychium spicatum
punarnava
commiphora
paederia foetida
smilax
tinospora cordifolia
rubia cordifolia
chaff flower
peony
lingusticum wallichii
prickly ash
myrrh
juniper berries
solomon's seal
siler root
flowering quince
dioscorea
teasel
eucommia
ganoderma
morinda
zanthoxylum
birch
queen of the meadow
polyphenols
anemarrhena asphodeloides
yucca
barrenwort
wintergreen
camphor oil
coix
gentiana macrophylla
noni
herbal blend (proprietary)
algae
cayenne pepper
ashitaba
gravel root
bladderwrack
arnica
clematis
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Aralia
Animal Tissue
Antler
Avian Cartilage
Achyranthes
Anamu
Avocado
Asteracea
Acetylsalicylic acid
Abuta
Amor seco
Animal protein
Bone
Black Seed
Baikal Skullcap
Bryonia
Biopeptide
Babchi
Bidens pilosa
Balsam
Bishop's Weed
Boswellic Acid
Bayleaf
Butea monosperma
Black galingale
Barleria
Bugbane
Baicalein
Bovine Protein
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Bogbean
Black Gram
Boswellia
Black Poplar
Black willow
Ba Ji Tian
Bone Protein
Bee products
Bombax
Borage
bovine cartilage / glycosaminoglycan
Baicalin
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Bee venom
Bergenia
Boerhavia diffusa
Curculigo orchicides
Comfrey
Centella triterpenes
Chinese Silkvine
Caryophyllene
Cinnamomum
Chinese Mountain Ant
Crustaceans
Cod Liver Oil
Coriander
Clerodendrum phlomidis
Cinquefoil
Cyathula
Curcuminoid
Capsaicin
Chuchuhuasi
Curcumen
Cymbopogon Martini
Centella asiatica
Cetylated Fatty Acids
Cissus sicyoides
Chicken
Curcuma
Calanus finmarchicus
Campsiandra angustifolia
Cowslip
Cannabidiol
Chebulinic acid
Carthamus
Copaiba Oil
Currant
Deer Root
Deer Velvet
Drynaria
Devil's Club
Dwarf Nettle
Dimethyl sulfoxide (DMSO)
Dipsacus
Elephant Vine
Egg
Elk antler
Emu Oil
Eicosapentaenoic Acid
Evening Primrose
Escin
Eucommia ulmoides
Ecklonia
Glycine
Glycosaminoglycans
Little ironweed
Products containing sarsaparilla
Nature's Sunshine CleanStart Mild
Nature's Sunshine Skin Detox (Ayurvedic)
Nature's Sunshine BP-X
Nature's Sunshine C-X
Nature's Sunshine DHEA-F
Nature's Sunshine DHEA-M
Nature's Sunshine Dieter's Cleanse
Nature's Sunshine Enviro-Detox
Nature's Sunshine Joint Support
Nature's Sunshine Menstrual Reg
Nature's Sunshine Natural Changes
Nature's Sunshine Structural System (30 Day Program)
Nature's Sunshine Thyroid Activator®
Nature's Sunshine Women's X-Action