Evidence supporting the use of: Evening primrose oil
For the body system: Joints
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Evening primrose oil (EPO) has been traditionally used to support joint health, largely due to its content of gamma-linolenic acid (GLA), an omega-6 fatty acid believed to have anti-inflammatory properties. Historically, EPO has been used in folk medicine for conditions involving inflammation, such as rheumatoid arthritis (RA). However, the scientific evidence supporting its efficacy for joint health is limited and inconsistent.
Some small clinical trials and observational studies have explored the effects of EPO on joint pain and stiffness, particularly in people with RA. While a few early studies suggested modest improvements in symptoms such as morning stiffness and pain reduction, subsequent and more rigorous research has failed to confirm significant or consistent benefits. Major health organizations, including the Arthritis Foundation and Cochrane Reviews, generally conclude that evidence is insufficient to recommend EPO as a reliable treatment for joint disorders.
In summary, the use of evening primrose oil for joint support is rooted in traditional practices and historical use rather than robust scientific validation. While some individuals may report subjective benefits, current clinical evidence does not strongly support its efficacy for joint health, and its use should be considered with caution, especially as an alternative to evidence-based therapies.
Other ingredients that support Joints
Alfalfaalgal oil
amino acids
berry flavor
beta caryophyllene
black cumin
black currant
sesame
borage oil
boron
Indian frankincense
bovine
bovine gelatin
broccoli
bromelain
burdock
cabbage leaf
calamari oil
cartilage
cat's claw
cherry
Chinese salvia root
chondroitin
cissus quadrangularis
collagen
turmeric
curcumin
cuspidatum root
devil's claw
dog rose
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fish oil
fish protein
flavonols
flaxseed
gamma linolenic acid (GLA)
gelatin
ginger
glucosamine
gokhru
gooseberry
gotu kola
green lipped mussel
guggul
horsetail
hyaluronic acid
Indian tinospora
knotweed
krill oil
L-proline
mackerel
manganese
marine lipid
methylsulfonylmethane (MSM)
microcrystalline hydroxyapatite concentrate (MCHC)
milk
moringa
mustard seed
n-acetyl-glucosamine
nettle
olive
omega-3 fatty acids
omega-6 fatty acids
phellodendron amurense
phytocannabinoids
pine bark
pineapple
plantain
protein
quercetin
rehmannia glutinosa
rhizome
rose hips
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
scrophularia root
serratiopeptidase
silicon
black ginger
specialized pro-resolving mediators (SPMs)
triphala
vitamin C
vitamin D
seaweed
water
white willow
wild yam
sarsaparilla
red clover
boneset
chickweed
gastrodia
capsicum
clerodendrum indicum
hedychium spicatum
punarnava
commiphora
paederia foetida
smilax
tinospora cordifolia
rubia cordifolia
chaff flower
peony
Szechuan lovage
prickly ash
myrrh
juniper berries
solomon's seal
siler root
flowering quince
dioscorea
teasel
eucommia
ganoderma
morinda
zanthoxylum
birch
queen of the meadow
polyphenols
anemarrhena asphodeloides
yucca
barrenwort
wintergreen
camphor oil
coix
gentiana macrophylla
noni
herbal blend (proprietary)
Algae
cayenne pepper
ashitaba
gravel root
bladderwrack
arnica
clematis
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Aralia
Animal Tissue
Antler
Avian Cartilage
Achyranthes
Anamu
Avocado
Asteracea
Abuta
Amor seco
Animal protein
Bone
Black Seed
Baikal Skullcap
Bryonia
Biopeptide
Babchi
Bidens pilosa
Balsam
Bishop's Weed
Boswellic Acid
Bayleaf
Butea monosperma
Black galingale
Barleria
Bugbane
Baicalein
Bovine Protein
berry
Bogbean
Black Gram
Boswellia
Black Poplar
Black willow
Ba Ji Tian
Bone Protein
Bee products
Bombax
Borage
bovine cartilage / glycosaminoglycan
Baicalin
Bassia scoparia
Bee venom
Bergenia
Boerhavia diffusa
Curculigo orchicides
Comfrey
Centella triterpenes
Chinese Silkvine
Caryophyllene
Cinnamomum
Chinese Mountain Ant
Crustaceans
Cod Liver Oil
Coriander
Clerodendrum phlomidis
Cinquefoil
Cyathula
Curcuminoid
Capsaicin
Chuchuhuasi
Curcumen
Cymbopogon Martini
Centella asiatica
Cetylated Fatty Acids
Cissus sicyoides
Chicken
Curcuma
Calanus finmarchicus
Campsiandra angustifolia
Cowslip
Cannabidiol
Chebulinic acid
Carthamus
Copaiba Oil
Currant
Deer Root
Deer Velvet
Drynaria
Devil's Club
Dwarf Nettle
Dimethyl sulfoxide (DMSO)
Dipsacus
Elephant Vine
Egg
Elk antler
Emu Oil
Eicosapentaenoic Acid
Evening Primrose Oil
European-Five Finger Grass
Escin
Eucommia ulmoides
Ecklonia
Figwort
Flavonoids
Fang-Feng
Fat liver oil
Fructoborate
Fish
Fatty acids
Flemingia philippinensis
Frankincense
Fir
Gnaphalium
Growth factors
Guaiac
Glycine
Garden Cress
Glycosaminoglycans
Guggulsterones
Golden Willow
Guazuma ulmifolia
Horse Gram
Heartsease
hydroxyproline
Hygrophila
Heal-All
Henna
Hairy Arnica
Harpagoside
Indian Nightshade
iridoids
Indian Sarsparilla
Iporuru
Indian Coraltree
Immortelle
Japanese Kadsura
Joe-Pye
Job's Tears
Kigelia africana
Kokilaksha
Knotgrass
Lithothamnion
Ledebouriella
Little ironweed
Loranthus
Ligusticum
Mezoneuron benthamianum
Mangiferin
Mineral ascorbate
Marjoram
Marsh Tea
Marine Protein
Mucopolysaccharide
Marine fat
Meadowsweet
Marking Nut Tree
Millettia
Nigella Seed
Nimbidin
Oroxylum indicum
Oxindole alkaloids
Osthole
Phellodendron
Puerarin
Premna
Pluchea
Prepared Aconite Tuber
Proteoglycans
Poplar
Pentacyclic triterpenoids
Proteolytic Enzymes
Polyunsaturated Fat
Phlomis umbrosa
Pansit-pansitan
portulaca
Polygonatum
Paeoniflorin
Physalis angulata
Pycnogenol
Polygonum
Petiveria
Plectranthus amboinicus
Palmitoylethanolamide (PEA)
Peptides
Qin Jiao
Rue
Rubus
Rockweed
Rosmarinic Acid
Rehmannia
Rhus coraria
Rubia yunnanensis
Rhus coriaria
Rhododendron
Sanicle
Sichuan Lovage
Silkmoth
Schizochytrium Oil
Stephania root
Sargentodoxa
Spanish Needle
Sausage Tree
Siegesbeckia
Smartweed
Shikonin
Salicin
Shellfish
Spiraea
Salmon Oil
Sida cordifolia
Spatholobus
Sinomenium acutum
Semecarpus anacardium
Stereospermum
Skunkvine
Sulfated polysaccharide
Sulfur
Sweet Bay
silica
Shilajit
Sargassum
Sassafras
Terminalia
Terpenoids
Tea
Thymoquinone
Tripeptide
Taxillus Sutchuenensis
Triterpenes
Taxillus chinensis
Tayuya
Tynanthus panurensis
Turmerones
Tasmannia lanceolata
Uraria picta
Uncaria
Vegetable Protein
Vladimiria souliei
Withanolides
Wrightia tinctoria
Willow
White Poplar
Willow Bracket
Zedoary
Other body systems supported by evening primrose oil
BreastsFemale Reproductive System
Joints
Ovaries
Prostaglandins
Reproductive System
Skin
Vagina
Products containing evening primrose oil
Nature's Sunshine Evening Primrose Oil
Nature's Sunshine Natural Changes
Nature's Sunshine Super GLA