Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Coix (Coix lacryma-jobi), also known as Job's tears or Yi Yi Ren, is traditionally used in East Asian medicine, particularly Traditional Chinese Medicine (TCM), to support joint health and address conditions such as rheumatism and arthritis. Modern scientific studies have begun to investigate these traditional claims. Coix seed extracts contain various bioactive compounds, including coixenolide, polysaccharides, and phenolic acids, which have demonstrated anti-inflammatory and analgesic properties in laboratory and animal studies. For example, research published in journals such as Phytotherapy Research and Journal of Ethnopharmacology has reported that coix seed extracts can inhibit pro-inflammatory cytokines and reduce joint swelling in animal models of arthritis. Some studies also indicate potential immune-modulating effects that could be relevant for autoimmune-related joint disorders. However, high-quality human clinical trials are limited, and most evidence comes from in vitro or animal research, or from studies using coix as part of multi-herb formulations, making it difficult to attribute effects solely to coix. Overall, the scientific evidence provides moderate support for the traditional use of coix in joint health, but more rigorous human studies are needed to confirm its efficacy and establish optimal dosing.

More about coix
More about Joints

Other ingredients that support Joints

Other body systems supported by coix

Products containing coix

Nature's Sunshine Kidney Activator TCM
Nature's Sunshine Kidney Activator (Chinese)