Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Evodia (Evodia rutaecarpa), known as Wu Zhu Yu in traditional Chinese medicine (TCM), has historically been used for a variety of ailments including digestive disorders, headaches, and abdominal pain. In some TCM formulations, Evodia is included as part of multi-herb prescriptions aimed at treating symptoms associated with jaundice, such as poor appetite, nausea, and digestive stagnation. The rationale in TCM is based on Evodia's ability to "warm the middle," dispel cold, and alleviate pain, rather than directly targeting bilirubin metabolism or liver function as understood in modern medicine. There is limited reference in classical TCM texts to the use of Evodia specifically for jaundice, and when used, it is typically in combination with other herbs that have more direct associations with liver and gallbladder health. Modern scientific studies investigating Evodia for jaundice in adults are lacking. Available research focuses mainly on its alkaloid components (e.g., evodiamine, rutaecarpine) for their potential anti-inflammatory, analgesic, or anti-cancer effects, rather than hepatoprotective or choleretic (bile-promoting) properties. There is insufficient clinical or preclinical evidence to validate its efficacy for jaundice treatment according to contemporary biomedical standards. In summary, the use of Evodia for jaundice is rooted primarily in traditional practices, with only indirect or weak evidence supporting its application for this specific condition, and virtually no modern scientific validation.

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