Evidence supporting the use of: Calotropis gigantea
For the health condition: Jaundice (adults)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Calotropis gigantea, commonly known as crown flower or "akanda," has been used in various traditional medicinal systems across Asia, including Ayurveda and folk medicine, for a range of ailments. Its use for jaundice (particularly in adults) is documented primarily in ethnobotanical surveys and traditional medicine texts, where preparations made from the leaves, roots, or latex have been recommended by practitioners. However, the documentation is largely anecdotal, and the plant is more widely noted for uses in treating skin diseases, digestive disorders, and as a purgative. Scientific studies investigating the efficacy and safety of Calotropis gigantea specifically for jaundice are minimal to nonexistent. While some preclinical studies have reported hepatoprotective effects of extracts from Calotropis species in animal models, these studies are preliminary, often not specific to jaundice, and do not provide robust clinical evidence for use in humans. Furthermore, the plant contains several potentially toxic compounds, such as cardiac glycosides, raising concerns about its safety profile. In summary, the use of Calotropis gigantea for jaundice is grounded in traditional practice, with very limited scientific support. Its application should be approached with caution due to potential toxicity and the lack of well-controlled human studies.

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