Evidence supporting the use of: Bupleurum (unspecified)
For the health condition: Jaundice (adults)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Bupleurum is primarily used for jaundice based on traditional medicine practices, particularly within Traditional Chinese Medicine (TCM). In TCM, Bupleurum root (commonly Bupleurum chinense or Bupleurum scorzonerifolium, known as "Chai Hu") is a key component in several classic herbal formulas, such as Xiao Chai Hu Tang (Minor Bupleurum Decoction). These formulas are traditionally prescribed for conditions described as "liver qi stagnation" and related syndromes, which often include symptoms interpreted as jaundice (e.g., yellowing of the skin and eyes, digestive disturbances).

Historical texts and TCM materia medica describe Bupleurum as having properties that "soothe the liver," "raise yang qi," and "harmonize the exterior and interior." It has been used in combination with other herbs to treat various types of jaundice, especially those associated with "damp-heat" in the liver and gallbladder.

However, scientific evidence supporting Bupleurum’s efficacy for adult jaundice is limited and largely preclinical. Some animal studies suggest potential hepatoprotective effects, but robust clinical trials in humans are lacking. Thus, its use for jaundice in adults is justified mainly by historical and traditional use, rather than modern scientific validation.

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