Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Boldo (Peumus boldus) has a long history of traditional use in South American herbal medicine, particularly in Chile, as a remedy for various digestive and liver disorders. Its use for jaundice is primarily rooted in folk medicine, where boldo leaves have been used as a cholagogue (to stimulate bile flow) and for their purported liver-protective effects. Historical texts and ethnobotanical accounts reference boldo as a treatment for symptoms associated with jaundice, such as yellowing of the skin and eyes, although these references are based on anecdotal and traditional practices rather than controlled scientific studies.

Modern scientific studies on boldo are limited and focus mostly on its effects on the digestive system and potential hepatoprotective properties in animal models. Some laboratory studies suggest that boldine, a key alkaloid in boldo, may have antioxidant and liver-protective effects, but there is no robust clinical evidence supporting its efficacy or safety for treating jaundice in adults. The evidence rating is low (1 out of 5), reflecting the predominance of traditional use over scientific validation. Health authorities generally do not endorse boldo for jaundice due to the lack of clinical trials and potential hepatotoxicity concerns with high or prolonged use. Therefore, while boldo is traditionally used for jaundice, its effectiveness and safety remain unproven in modern medicine.

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