Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Barleria spp., particularly Barleria prionitis, have traditionally been used in various forms of folk and Ayurvedic medicine to support liver health and treat jaundice in adults. Historical records and ethnobotanical surveys indicate that different parts of the plant—primarily leaves and roots—are employed in decoctions or pastes for managing jaundice, likely due to their perceived hepatoprotective and anti-inflammatory properties. However, while these traditional uses are well-documented in texts and surveys, scientific validation remains limited. A small number of preclinical studies suggest Barleria extracts may possess antioxidant and hepatoprotective effects in animal models, but there is a lack of robust clinical trials in humans specifically addressing jaundice. The mechanism proposed in traditional contexts is generally non-specific: plants with bitter principles or anti-inflammatory effects are often chosen for liver ailments. In summary, the use of Barleria for jaundice is justified by its longstanding traditional use in South Asian herbal systems, but the scientific evidence is preliminary and insufficient for strong recommendation.

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