Waltheria ovata is traditionally used in various parts of Africa and tropical regions for the management of skin conditions, including itching (pruritus). Ethnobotanical surveys and traditional medicine records document its application as a topical remedy to soothe skin irritation, rashes, and itching, often in the form of poultices or decoctions. The use is primarily based on cultural and historical practices rather than rigorous scientific validation.

The evidence supporting its use for itching is largely anecdotal, derived from local healers and community practices. Some preliminary phytochemical analyses of related Waltheria species (such as Waltheria indica) have identified the presence of flavonoids, alkaloids, and other compounds with possible anti-inflammatory and antioxidant activities, which could theoretically contribute to the relief of itching. However, there is a lack of direct clinical studies or robust preclinical data specifically evaluating Waltheria ovata for pruritus.

In summary, the use of Waltheria ovata for itching is justified by tradition rather than strong scientific evidence. While its ethnomedicinal role is well-documented, the current scientific evidence base is weak, and more research is needed to substantiate its effectiveness and safety for this indication.