Evidence supporting the use of: Vitamin D
For the health condition: Itching

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin D has some scientific evidence supporting its use in the management of itching (pruritus), particularly in cases associated with certain dermatological conditions. Research indicates that vitamin D plays a role in immune modulation and skin barrier function, which are relevant in disorders where pruritus is a key symptom, such as atopic dermatitis and psoriasis. Several small-scale randomized controlled trials and observational studies have shown that vitamin D supplementation or topical analogs (like calcipotriol) can reduce itch severity in these specific patient populations. For instance, topical vitamin D analogs are commonly used in the treatment of psoriasis, where they help modulate skin cell proliferation and inflammation, indirectly reducing itch. Some studies have also noted benefit in patients with chronic kidney disease-associated pruritus who often have low vitamin D levels. However, the evidence is not robust across all causes of itching, and vitamin D is not universally recommended as a first-line therapy for generalized pruritus. Its benefit seems to be limited to particular subgroups where deficiency or specific pathophysiology is involved. Large-scale, high-quality trials are lacking, and the effect size is generally modest. Therefore, while there is a scientific rationale and some supportive data, vitamin D should not be considered a primary treatment for itching outside of these specific contexts. Supplementation is best guided by documented deficiency or underlying disease processes where evidence exists.

More about vitamin D
More about Itching

Other ingredients used for Itching

Abrus
Agrimony
Allantoin
Aloe vera
Alstonia scholaris
American Liverleaf
Amor seco
anamu
apple cider vinegar
Arani
argan nut oil
Arisaema
Asam gelugor
Asarum sieboldii
avens
babchi
Baliospermum
balsam
Baphicacanthus cusia
Barleria
bentonite
betel
black nightshade
Brazilian peppertree
cajuput
calamus
Calendula
Calotropis gigantea
camphor oil
carry me seed
Carthamus
castor oil
catechu
cedar
chamomile
chickweed
cinquefoil
citronella
Clerodendrum trichotomum
cocoa butter
coconut oil
colloid
copaiba oil
cornflower
Cyanthillium cinereum
Davilla rugosa
dendramine
Didymocarpus
divi-divi
Dwarf Nettle
elephant\'s head
emu oil
Erodium cicutarium
eugenol
Euphorbia
European Elder
fang-feng
ferula assafoetida
fleabane
Flueggea suffruticosa
fringed pink
Gardenia jasminoides
geranium
giant blazingstar
golden shower tree
henna
Homalomena
honey loquat syrup
Houttuynia
Hydrocolloid
Indian nightshade
Japanese sophora
Jessica\'s sticktight
Jewelweed
jojoba oil
labrador tea
Lantana camara
Ledebouriella
Leptospermum scoparium
Lesser speargrass
lichen
licorice root
Lophira lanceolata
Lycopodium
Lysimachia
Macaranga indica
Mahonia
mallow
Malva sylvestris
Marking Nut Tree
Marsh Tea
Marshmallow
Matapalo Tree
Matico
melaleuca alternifolia
Myrobalan
Oak
Onosma bracteatum
oriental arborvitae
pagoda tree
Pellitory
Pepper Bark Tree
Peppermint
Plectranthus amboinicus
Plumbago zeylanica
Polygonum
Potentilla
Pulsatilla
Quisqualis
Rhus glabra
Rubus
rue
Sabadilla
Sagebrush
Salvia
Sandalwood
Sandy Everlasting
Sanguisorba
Sapindus mukorossi
Scabrous Gentian
scrophularia root
Self-Heal
Semiaquilegia
Sensitive Plant
sheep's sorrel
Slippery Elm
slippery elm bark
Snakeroot
Soapberry
Southernwood
Spanish Needle
Speedwell
Spikenard
Spilanthes
Storax
Sumac
Sweet Annie
Sweet Bay
sweetgums
Tannins
Tea Tree Oil
Terpinen-4-ol
Thymol
turmeric
typhonium
Vervain
vitamin D
vitamin E
Waltheria ovata
White oak
Winter Savory
Witch Hazel
Wrightia tinctoria
Yarrow
Zinc

Other health conditions supported by vitamin D

Acne
Allergies (food)
Allergies (respiratory)
Alzheimer's Disease
Amenorrhea
Anemia
Anorexia
Apathy
Arrhythmia
Arteriosclerosis
Arthritis
Asthma
Autism
Autoimmune Disorders
Backache
Birth Defects (prevention)
Body Building
Broken Bones
Calcium Deficiency
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Celiac Disease
Chronic Obstructive Pulmonary Disorder
Colds (antiviral)
Colds (general)
Colds (prevention)
Colds (with fever)
Concentration (poor)
Concussions
Confusion
Congestive Heart Failure
Contagious Diseases
Convalescence
Convulsions
Cramps (menstrual)
Cramps and Spasms
Crohn's Disease
Cystic Breast Disease
Cystic Fibrosis
Dandruff
Debility
Dementia
Depression
Dermatitis
Diabetes
Diabetic Retinopathy
Erectile Dysfunction
Estrogen (low)
Fatigue
Fibroids (uterine)
Fibromyalgia Syndrome
Fibrosis
Grave's Disease
Grief and Sadness
Hair (loss or thinning)
Hair Care (general)
Hashimoto's Disease
Headache (cluster)
Heart (weakness)
Hypertension
Hypothyroid
Infection
Infection (bacterial)
Infection (viral)
Infertility
Inflammation
Inflammatory Bowel Disorders
Influenza
Injuries
Irritable Bowel Syndrome
Itching
Knees (weak)
Leaky Gut Syndrome
Leprosy
Lesions
Leukemia
Lou Gehrig's Disease
Lupus
Lymphoma
Melanoma
Memory and Brain Function
Menopause
Menstrual Irregularity
Mental Illness
Metabolic Syndrome
Migraine
Miscarriage (prevention)
Mood Swings
Multiple Sclerosis
Muscle Tone (lack of)
Muscular Dystrophy
Myasthenia Gravis
Nephritis
Nerve Damage
Nervous Exhaustion
Numbness
Nursing
Obsessive Compulsive Disorder
Oral Surgery
Osteoporosis
Pain (general remedies for)
Pancreatitis
Paralysis
Parkinson's Disease
Peripheral Neuropathy
PMS (general)
PMS Type D
PMS Type H
PMS Type P
PMS Type S
Pneumonia
Polyps
Post Partum Depression
Post Partum Weakness
Pregnancy (herbs and supplements for)
Progesterone (low)
Prostatitis
Psoriasis
Rheumatoid Arthritis
Schizophrenia
Sciatica
Seasonal Affective Disorder
Senility
Tuberculosis