Paraffin wax is commonly used in dermatological and physical therapy settings, particularly as a component of paraffin wax baths. While paraffin wax itself is not a direct antipruritic (anti-itch) agent, its use is supported by scientific evidence for improving skin hydration and barrier function, which can indirectly alleviate itching, especially in conditions characterized by dry or rough skin (xerosis, eczema, psoriasis). Clinical studies have demonstrated that paraffin wax treatments can significantly increase skin moisture and reduce scaling, thereby lessening itch associated with dryness. For example, research has shown that patients with hand eczema or chronic dry skin experienced symptomatic relief, including reduced pruritus, after regular paraffin wax therapy.

The mechanism is primarily through occlusion: the warm, melted wax forms a coating on the skin, trapping moisture and promoting absorption of water into the stratum corneum. This improved hydration reduces transepidermal water loss and soothes irritation that leads to itching. However, paraffin wax does not have specific antipruritic chemical properties and is not indicated for itching caused by allergic reactions, infections, or systemic conditions. Its role is limited to symptomatic relief in dryness-associated itch, and while evidence is moderate, it is recognized in clinical guidelines for supportive skin care.

In summary, paraffin wax is scientifically validated as a supportive treatment for itch secondary to dry skin, with moderate-quality evidence (rated 3 out of 5), but not as a primary antipruritic.