Evidence supporting the use of: Japanese sophora
For the health condition: Itching

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Japanese sophora (Sophora japonica), also known as Huai Hua in traditional Chinese medicine (TCM), has a long history of use in East Asian herbal medicine. Traditionally, extracts from its flower buds have been employed to treat various conditions, including bleeding disorders, inflammation, and skin problems such as itching (pruritus). The rationale in TCM is that Japanese sophora "clears heat" and "cools the blood," which are believed to be underlying causes of skin irritations and itching in traditional diagnostic frameworks. Historical texts and pharmacopeias, such as the "Compendium of Materia Medica," mention its use for skin conditions.

Modern scientific evidence for Japanese sophora’s efficacy specifically in treating itching is limited. Some studies have investigated its anti-inflammatory and antioxidant properties, primarily attributed to its rich content of flavonoids like rutin and quercetin. These compounds may, in theory, help modulate inflammatory responses involved in itching. However, direct clinical studies evaluating its effectiveness for pruritus in humans are scarce.

In summary, while Japanese sophora has traditional backing for use in treating itching, especially within TCM contexts, robust clinical evidence is lacking. Its use for this purpose remains grounded more in historical practice than in modern scientific validation.

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