Evidence supporting the use of: Cyanthillium cinereum
For the health condition: Itching

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Cyanthillium cinereum, also known as Little Ironweed, has a history of use in traditional medicine systems in parts of Asia for the management of various skin conditions, including itching (pruritus). Folk practices in India, Thailand, and other Southeast Asian countries have utilized topical preparations or decoctions of the plant to alleviate discomfort from skin irritations, likely due to its perceived anti-inflammatory and soothing properties. However, scientific validation for its specific efficacy against itching is limited. A few in vitro and animal studies have demonstrated that extracts from Cyanthillium cinereum possess anti-inflammatory and antioxidant activity, which could theoretically contribute to its use for pruritic conditions, but direct clinical evidence in humans is lacking. The traditional use likely stems from empirical observation and the general application of anti-inflammatory herbs for skin complaints rather than targeted anti-pruritic research. Overall, while there is a traditional basis for its use in itching, the supporting evidence from modern scientific research is weak, and more rigorous clinical studies are needed to substantiate its effectiveness and safety for this particular indication.

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