Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Colloids, particularly colloidal oatmeal (Avena sativa), are scientifically validated for use in the treatment of itching (pruritus). Colloidal oatmeal is a well-established ingredient in dermatology for its soothing, anti-inflammatory, and protective properties. Numerous clinical studies and reviews have demonstrated its efficacy in conditions associated with itching, such as atopic dermatitis, xerosis (dry skin), and other eczematous disorders. The mechanism of action is attributed to several bioactive compounds in oatmeal, including avenanthramides, which exhibit anti-inflammatory and antioxidant effects, as well as beta-glucans, which help maintain skin hydration and barrier function. The U.S. Food and Drug Administration (FDA) recognizes colloidal oatmeal as a skin protectant, and it is a common ingredient in over-the-counter creams, lotions, and bath treatments for pruritus. However, the term "colloid (unspecified)" could technically refer to a variety of colloidal substances, not all of which have proven efficacy for itching. Therefore, the strong scientific evidence applies primarily to colloidal oatmeal. For other unspecified colloids, evidence may be lacking or absent. In summary, for colloidal oatmeal, there is a robust scientific basis supporting its use for the relief of itching, with endorsements from regulatory agencies and clinical guidelines.

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