Synopsis

Source of validity: Traditional
Rating (out of 5): 1

American Liverleaf (Hepatica americana), also known as liverwort, has a history of use in North American traditional herbal medicine, especially among Native American groups and early European settlers. Its leaves were sometimes used in teas or poultices to address a variety of ailments, including liver complaints, digestive issues, and skin irritations such as itching. However, documentation of its use specifically for itching is sparse and mostly anecdotal, often rooted in the "Doctrine of Signatures," where plants resembling certain body parts were thought to treat ailments of those organs or tissues. There is no robust ethnobotanical or historical record that systematically supports its efficacy for itching, but it was occasionally part of folk remedies for skin issues.

From a scientific standpoint, there is no modern clinical evidence or pharmacological research validating the use of American Liverleaf for itching or pruritus. No controlled studies or published clinical trials have assessed its effectiveness for this condition, and active constituents that could mediate anti-itch effects have not been clearly identified or studied in relevant models. Thus, its use for itching remains primarily traditional and is supported by very limited, low-quality evidence.

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