Evidence supporting the use of: Senna
For the health condition: Irritable Bowel Syndrome
Synopsis
Source of validity: Traditional
Rating (out of 5): 1
Senna is a herbal laxative traditionally used to treat constipation. Its use in Irritable Bowel Syndrome (IBS) is rooted more in tradition than in scientific evidence, particularly for IBS subtypes characterized by constipation (IBS-C). Historically, senna leaves and pods have been used in various cultures as a remedy for sluggish bowels due to their active compounds called sennosides, which stimulate intestinal motility and promote bowel movements.
However, the evidence supporting senna’s efficacy specifically for IBS is weak. Most clinical studies on senna focus on its laxative effect in general constipation, not IBS. While some IBS patients with predominant constipation may experience relief from senna, there is little direct scientific research on its safety or effectiveness for IBS overall. In fact, its stimulant effect may be too harsh for some IBS patients, potentially causing cramping, diarrhea, or worsening bowel irregularity, especially in those with mixed or diarrhea-predominant IBS.
Major gastroenterology guidelines do not recommend senna as a first-line treatment for IBS. Instead, they typically suggest lifestyle modifications, dietary fiber, or other medications with more established evidence. In summary, senna’s use in IBS is based on traditional use as a laxative, but lacks robust scientific validation for this specific condition.
Other ingredients used for Irritable Bowel Syndrome
2'-Fucosyllactoseakkermansia muciniphila
aloe vera
alpha-galactosidase
alpha-pinene
amino acids
bacillus clausii
bacillus coagulans
bacillus subtilis
benegut perilla (proprietary)
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
bilberry
bio ecolian (proprietary)
blackberry
Indian frankincense
butyrate triglyceride
chen pi
chia seed
chlorella
cinnamon
turmeric
curcumin
fennel
flaxseed
fructooligosaccharides (FOS)
fruit and vegetable blend (proprietary)
ginger
green banana
green tea
guar gum
cellulose
inulin
isomalto-oligosaccharide
l-glutamine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus casei
lactobacillus fermentum
lactobacillus gasseri
lactobacillus helveticus
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
lovage
marshmallow
oat
pectin
peppermint oil
plum fruit
pomegranate
potato starch
butyric acid
psyllium
quercetin
resveratrol
saccharomyces boulardii
slippery elm bark
spearmint leaf
streptococcus thermophilus
tributyrin
vitamin D
xylooligosaccharides
zinc
hyssop
atractylodes
ferula assafoetida
anise
holarrhena antidysenterica
fumaria parviflora
chrysanthemum
senna
white oak
algae
Agastache
Asafoetida
Alexandrian senna
Agrimonia pilosa
Betony
Bifidobacterium
Bacillus indicus
Bifidobacterium adolescentis
Boswellic Acid
Bayleaf
Belleric myrobalan
Bran
Boswellia
Bacillus licheniformis
black salt
Bifidobacterium animalis
Bitter principals
Bacteria
Bifidobacteria
Bacillus
Cumin
Coriander
Citron
Cannabidiol
Clerodendrum indicum
Dragonhead
Dichrostachys glomerata
Enterococcus
Enzyme Blend
Fig
Fiber
Frangula
Glucooligosaccharides
Galactomannan
Galactooligosaccharides
Quince
Rhubarb
Other health conditions supported by senna
Colon (atonic)Constipation (adults)
Constipation (children)
Digestion (poor)
Irritable Bowel Syndrome
Products containing senna
Nature's Sunshine LB Extract
Nature's Sunshine Liquid Cleanse
Nature's Sunshine Senna Combination