Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Cellulose, specifically in the form of powdered cellulose or as the primary component of insoluble fiber supplements, has a foundation of scientific validation for use in certain cases of Irritable Bowel Syndrome (IBS), particularly IBS with constipation (IBS-C). Insoluble fiber like cellulose increases stool bulk and can promote more regular bowel movements, which may help alleviate constipation-predominant symptoms in IBS patients. Several clinical guidelines, including those from gastroenterology associations, recommend the cautious use of insoluble fiber for constipation, though soluble fiber (like psyllium) is generally preferred because insoluble fibers can sometimes exacerbate bloating and abdominal discomfort in sensitive individuals.

A number of controlled trials have examined the effects of dietary fiber supplementation in IBS. While results are mixed, meta-analyses confirm that fiber can improve global IBS symptoms, with insoluble fiber being less effective overall than soluble forms. Cellulose, as a purified insoluble fiber, is sometimes included in studies and over-the-counter fiber products. Clinical guidance typically suggests starting with low doses and increasing gradually to minimize potential side effects. However, it is important to note that not all IBS patients benefit from cellulose supplementation, and for some, symptoms may worsen.

In summary, the use of cellulose for IBS is scientifically justified for select cases, especially IBS-C, but the evidence is moderate rather than strong. It is not considered a universal solution for all types of IBS, and clinical guidance emphasizes an individualized approach.

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