Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Bupleurum species, particularly Bupleurum chinense, have a long history of use in Traditional Chinese Medicine (TCM). They are commonly included in herbal formulas such as Xiao Chai Hu Tang, which are traditionally prescribed for various digestive ailments, including symptoms that may overlap with modern concepts of Irritable Bowel Syndrome (IBS)—such as abdominal pain, bloating, and irregular bowel movements. The rationale in TCM for using Bupleurum often relates to its ability to "soothe the liver" and regulate qi (energy flow), which are thought to influence digestive function and gut motility.

Despite this traditional usage, there is very limited direct scientific evidence supporting Bupleurum specifically for the treatment or management of IBS. Most available studies focus on its anti-inflammatory, hepatoprotective, and immunomodulatory effects, rather than direct clinical trials in IBS populations. A few animal studies suggest potential effects on gut motility and inflammation, but these findings are preliminary and not robustly supported in human clinical trials.

In summary, the use of Bupleurum for IBS is primarily justified by traditional use rather than strong scientific validation. The current evidence base for its efficacy in IBS is weak, and further research—especially well-designed human clinical trials—is required to establish its effectiveness for this condition.

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