Evidence supporting the use of: Bitter principals
For the health condition: Irritable Bowel Syndrome
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Bitter principles, also known as bitters, refer to a class of plant-based compounds that have a distinctly bitter taste and are commonly found in herbs such as gentian, dandelion, and wormwood. The use of bitters to support digestion and gastrointestinal health, including symptoms now classified as Irritable Bowel Syndrome (IBS), has a long tradition in European and Asian herbal medicine. Their historical use is based on the belief that the bitter taste stimulates digestive secretions, enhances appetite, and improves gut motility.
However, while bitters have centuries of traditional use for "dyspepsia," "indigestion," and "sluggish digestion," the direct application to IBS is less clearly documented in historical texts, as IBS is a modern medical diagnosis. Some traditional texts describe the use of bitters for symptoms like bloating, flatulence, and irregular bowel movements, which overlap with IBS.
Scientific evidence for the use of bitters in IBS specifically is limited. A few small studies suggest that bitters can increase saliva and gastric juice production, supporting digestion in general, but robust clinical trials for IBS are lacking. Systematic reviews and clinical guidelines do not currently endorse bitters as a first-line or evidence-based therapy for IBS. Thus, their use for IBS is justified mostly by tradition, with modest supporting evidence for general digestive benefit but not specifically for IBS.
More about Bitter principals
More about Irritable Bowel Syndrome
Other ingredients used for Irritable Bowel Syndrome
2'-Fucosyllactoseakkermansia muciniphila
aloe vera
alpha-galactosidase
alpha-pinene
amino acids
bacillus clausii
bacillus coagulans
bacillus subtilis
benegut perilla (proprietary)
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
bilberry
bio ecolian (proprietary)
blackberry
Indian frankincense
butyrate triglyceride
chen pi
chia seed
chlorella
cinnamon
turmeric
curcumin
fennel
flaxseed
fructooligosaccharides (FOS)
fruit and vegetable blend (proprietary)
ginger
green banana
green tea
guar gum
cellulose
inulin
isomalto-oligosaccharide
l-glutamine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus casei
lactobacillus fermentum
lactobacillus gasseri
lactobacillus helveticus
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
lovage
marshmallow
oat
pectin
peppermint oil
plum fruit
pomegranate
potato starch
butyric acid
psyllium
quercetin
resveratrol
saccharomyces boulardii
slippery elm bark
spearmint leaf
streptococcus thermophilus
tributyrin
vitamin D
xylooligosaccharides
zinc
hyssop
atractylodes
ferula assafoetida
anise
holarrhena antidysenterica
fumaria parviflora
chrysanthemum
senna
white oak
algae
Agastache
Asafoetida
Alexandrian senna
Agrimonia pilosa
Betony
Bifidobacterium
Bacillus indicus
Bifidobacterium adolescentis
Boswellic Acid
Bayleaf
Belleric myrobalan
Bran
Boswellia
Bacillus licheniformis
black salt
Bifidobacterium animalis
Bitter principals
Bacteria
Bifidobacteria
Bacillus
Cumin
Coriander
Citron
Cannabidiol
Clerodendrum indicum
Dragonhead
Dichrostachys glomerata
Enterococcus
Enzyme Blend
Fig
Quince
Rhubarb
Other health conditions supported by Bitter principals
Acid IndigestionAppetite (deficient)
Belching
Colds (general)
Colic (adults)
Colic (children)
Constipation (adults)
Digestion (poor)
Dyspepsia
Gall Bladder (sluggish or removed)
Gas and Bloating
Gastritis
Indigestion
Infection
Inflammation
Irritable Bowel Syndrome
Liver Detoxification
Nausea and Vomiting
Sugar Cravings
Ulcers
Wounds and Sores