Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bacillus species, particularly Bacillus coagulans and Bacillus subtilis, are spore-forming probiotics that have been studied for their potential benefits in gastrointestinal disorders, including Irritable Bowel Syndrome (IBS). Several small-scale clinical trials and a few meta-analyses suggest that supplementation with certain Bacillus strains may help alleviate some IBS symptoms, such as bloating, abdominal pain, and irregular bowel movements. For example, randomized controlled trials have reported modest improvements in global IBS symptoms and quality of life when Bacillus-based probiotics are used, either alone or in combination with other probiotic strains. The proposed mechanisms include modulation of the gut microbiota, enhancement of intestinal barrier function, and anti-inflammatory effects. However, the overall quality and quantity of the evidence remain limited. Most studies involve small sample sizes, heterogeneity in Bacillus strains and formulations, and short study durations. Systematic reviews, including those published up to 2023, typically find that while Bacillus probiotics are generally safe and may offer mild benefit, the certainty of evidence is low to moderate at best. As such, while there is some scientific validation for the use of Bacillus (mixed) in IBS, the evidence is not robust enough to support strong or universal recommendations, and more large-scale, high-quality trials are needed to establish efficacy with confidence.

More about Bacillus (mixed)
More about Irritable Bowel Syndrome

Other ingredients used for Irritable Bowel Syndrome

Other health conditions supported by Bacillus (mixed)

Products containing Bacillus (mixed)