Evidence supporting the use of: Valerian root
For the health condition: Irritability

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Valerian root has a long history of traditional use as an herbal remedy for a variety of nervous system complaints, including irritability, anxiety, and insomnia. The use of valerian dates back to ancient Greece and Rome, where it was described as a remedy for restlessness and emotional disturbances. Traditional herbal medicine systems in Europe and Asia have recommended valerian root for calming purposes and to soothe mood-related symptoms such as irritability.

However, scientific evidence specific to valerian’s effects on irritability is limited. Most clinical studies have focused on its sedative and anxiolytic properties, primarily in the context of sleep disorders and generalized anxiety symptoms. Some small studies and anecdotal reports suggest that by improving sleep quality and reducing anxiety, valerian may indirectly help with irritability, especially when irritability is linked to poor sleep or heightened nervous tension. The active compounds in valerian, such as valerenic acids and volatile oils, are thought to interact with gamma-aminobutyric acid (GABA) receptors in the brain, producing mild calming effects.

Despite its traditional use, there is insufficient direct scientific evidence to robustly support valerian as a treatment specifically for irritability. More targeted research is needed to determine its efficacy for this particular symptom. Nonetheless, its historical use for calming nerves and alleviating restlessness explains why valerian root is still sometimes used to support individuals experiencing irritability.

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