Evidence supporting the use of: Vitamin B6
For the health condition: Insomnia

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Vitamin B6 (pyridoxine) has traditionally been used as a supportive ingredient for insomnia, largely based on its role in neurotransmitter synthesis. Historically, some practitioners and traditional health systems have recommended vitamin B6 supplementation to help with sleep, under the rationale that it is involved in the production of serotonin and melatonin—both of which play crucial roles in regulating sleep cycles. However, scientific validation for its effectiveness in treating insomnia is limited and generally weak.

Some small studies and anecdotal reports have suggested that B6, especially when combined with other supplements like magnesium, may improve sleep quality or reduce the time it takes to fall asleep. However, larger, more rigorous clinical trials are lacking, and the evidence remains inconclusive and sometimes contradictory. The few studies that do exist often use B6 as part of a multinutrient or complex intervention, making it difficult to isolate its individual effects.

Overall, while there is a plausible mechanism (supporting neurotransmitter synthesis), the current body of scientific evidence does not robustly support the use of vitamin B6 as a standalone treatment for insomnia. Therefore, its use is best characterized as traditional, with limited scientific backing.

More about vitamin B6
More about Insomnia

Other ingredients used for Insomnia

5-Hydroxytryptophan (5-HTP)
Agarwood
Agastache
Agrimonia pilosa
Albizia
Alpha lactalbumin
alpha-terpineol
amber
amino acids
anamu
anemarrhena asphodeloides
Anemone
Angelica
anise
apigenin
Aralia
Arani
ashwagandha
aster root
atractylone
Baikal Skullcap
balsam
banyan
bayleaf
benegut perilla (proprietary)
betony
big quaking grass
black cumin
black seed
blackboard tree
blackthorn
Borassus aethiopum
borassus palm
brahmi
Bupleurum
cactus
calamus
calcium
Calea zacatechichi
California poppy
cannabidiol
cannabinol
Capitate Valerian
carry me seed
Carthamus
cassia bark
catnip
Centella asiatica
Centella triterpenes
chamomile
cherimoya
cherry
Chinese salvia root
Chinese silkvine
chrysanthemum
cinnamon
citron
Clary sage
Clerodendrum indicum
Clerodendrum trichotomum
Coptis chinensis
corktree
Corydalis
cowslip
Cyathula
Cymbopogon martini
David\'s milkberry
Doxylamine succinate
dragonhead
elephant\'s head
elk antler
Embelia
Erodium cicutarium
European Elder
fennel
Ficus religiosa
Ficus simplicissima
Flueggea suffruticosa
frankincense
fringed pink
GABA (gamma aminobutyric acid)
ganoderma
Gardenia jasminoides
Gelsemium
geraniol
giant blazingstar
Glycine
goji berry
gooseberry
gotu kola
Greek mountain tea
heartwood
Homalomena
honeybush
hops
Indian frankincense
jasmine
Jatamansi
Jatoba
jujube
jujubosides
kava
kavalactones
kiwi
kudzu
Kukicha
L-tryptophan
labrador tea
lactium casein decapeptide
Lactucarium
Lady of the Night
Large-leaved linden
lavender
lemon balm
Lesser speargrass
Lilium polyphyllum
lily
linalool
linden
Lindera
lingzhi
little ironweed
longan
loquat
Loranthus
lotus
lotus seed
lupulinum
Lycium
maca
Macaranga indica
mace
magnesium
magnolia
magnolol
mallow
Marine lipid
Marjoram
Matapalo Tree
Melatonin
Mesua
Microtea debilis
Milk Protein
Mimosa
Moringa
Morning glory
Morus
Motherwort
Mulungu
Myrcene
Nardostachys
Night jessamine
Nymphaea caerulea
Nymphaea nouchali
Onosma bracteatum
Ophiopogon
ophiopogon root
orange
orchid
Oroxylum indicum
Osmanthus
Osthole
paeoniflorin
passionflower
Passionfruit
Patchouli oil
peach
perilla
Persimmon
phlorotannins
phytocannabinoids
Pimpinella
pollen
Polygala
polygala root
Polygonatum
Polygonum
polysaccharides
poppy
Portulaca
Premna
Pulsatilla
purslane
quail egg
Rauvolfia
reishi mushroom
rice
Rooibos
rose
rose oil
Rubiaceae
rue
saffron
Safranal
sage
Salvia
Sandalwood
Sarivan
Schisandrins
Scoparia dulcis
scrophularia root
Sedanenolide
Self-Heal
Semecarpus anacardium
Sensitive Plant
Shankhpushpi
silk tree
skullcap
soursop
Southernwood
Speedwell
Spikenard
Stachytarpheta cayennensis
Sumac
Sumbul
Sweet Annie
Sweet Bay
Sweet Orange alcohol
Sweet Woodruff
Sword Bean
Szechuan lovage
Tagara
Terminalia
Tetrahydropalmatine
Valerenic acid
Valerian root
Verbena
Vervain
Vetiver
vitamin B6
Walnut
Waterhyssop
Wax Gourd
Winter Begonia
Winter Savory
Withanolides
Wood betony
Yellow-Fruit Nightshade
Ylang ylang
Yuzu
Zinc

Products containing vitamin B6

Nature's Sunshine Love and Peas (Sugar Free Original Formula)
Nature's Sunshine 5-HTP Power
Nature's Sunshine Adrenal Support
Nature's Sunshine AIVIA Clean Energy
Nature's Sunshine AIVIA Plant Protein
Nature's Sunshine AIVIA Plant Protein
Nature's Sunshine AIVIA Whey Protein
Nature's Sunshine AIVIA Whey Protein
Nature's Sunshine Balanced B Complex (Vitamin B)
Nature's Sunshine Cardio Assurance
Nature's Sunshine Children's MultiVitamin & Mineral
Nature's Sunshine Glandular System
Nature's Sunshine Heavy Metal Detox
Nature's Sunshine Liquid - Methyl Vitamin B-12 Complete
Nature's Sunshine Love and Peas (Sugar Free) NEW!
Nature's Sunshine Love and Peas
Nature's Sunshine Mega-Chel
Nature's Sunshine MultiVitamin & Mineral (SynerPro)
Nature's Sunshine MultiVitamin & Mineral (Time Release)
Nature's Sunshine Natural Changes
Nature's Sunshine Nature's Prenatal
Nature's Sunshine Nature's Harvest
Nature's Sunshine Nervous System (30 Day Program)
Nature's Sunshine Nutri-Calm
Nature's Sunshine Nutri-Calm
Nature's Sunshine Power Beets Pouch
Nature's Sunshine Power Beets To-Go Packs
Nature's Sunshine Power Greens Pouch
Nature's Sunshine Power Greens To-Go
Nature's Sunshine Power Meal Chocolate
Nature's Sunshine Power Meal Vanilla
Nature's Sunshine Skeletal Strength
Nature's Sunshine Solstic Twenty-Four
Nature's Sunshine Solstic Energy
Nature's Sunshine Solstic Revive
Nature's Sunshine Structural System (30 Day Program)
Nature's Sunshine Super Supplemental
Nature's Sunshine Super Supplemental (Without Iron)
Nature's Sunshine Super Trio
Nature's Sunshine Thyroid Support
Nature's Sunshine B-Complex
Nature's Sunshine Vitamin B6
Nature's Sunshine VitaWave