Evidence supporting the use of: Premna
For the health condition: Insomnia
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Premna, particularly species such as Premna serratifolia, has a long history of use in traditional medicine systems across Asia, including Ayurveda, Siddha, and traditional Chinese medicine. In these systems, Premna leaves and roots are used for their purported calming and sedative effects, and are sometimes included in herbal formulations aimed at supporting restful sleep and treating insomnia. The basis for this use is largely empirical and rooted in centuries of traditional practice rather than rigorous scientific evaluation.
Scientific studies investigating Premna species for insomnia or sleep disorders are extremely limited. A small number of animal studies suggest that extracts from Premna may have central nervous system depressant activity, potentially contributing to sedative effects, but these findings are preliminary and not directly tied to clinical outcomes in humans. There are no high-quality clinical trials validating its efficacy or safety for insomnia in humans. Thus, while Premna is traditionally used to support sleep and treat insomnia, robust scientific evidence is lacking, and its use for this purpose should be considered as based primarily on tradition, with a low to moderate level of empirical support.
Other ingredients used for Insomnia
5-Hydroxytryptophan (5-HTP)amino acids
ashwagandha
waterhyssop
benegut perilla (proprietary)
black cumin
Indian frankincense
rice
calcium
California poppy
cassia bark
chamomile
cherry
Chinese salvia root
cinnamon
Coptis chinensis
fennel
GABA (gamma aminobutyric acid)
gooseberry
gotu kola
greek mountain tea
heartwood
hops
jujube
kava root
kudzu
l-tryptophan
lactium casein decapeptide
lavender
maca
magnesium
magnolia
marine lipid
melatonin
moringa
motherwort
ophiopogon root
orange
passionflower
perilla
phytocannabinoids
pollen
polygala root
quail egg
reishi mushroom
rose oil
saffron
sage
scrophularia root
skullcap
valerian root
vitamin B6
zinc
catnip
tangerine
anise
blackboard tree
lingzhi
lingusticum wallichii
morus
silk tree
chrysanthemum
amber
ganoderma
lotus seed
anemarrhena asphodeloides
purslane
aster root
peach
wood betony
goji berry
soursop
Aralia
Agastache
Alpha-terpineol
Angelica
Apigenin
Anamu
Albizia
Agarwood
Anemone
Alpha lactalbumin
Agrimonia pilosa
Arani
Atractylone
Betony
Black Seed
Baikal Skullcap
Blackthorn
Balsam
Bayleaf
Big Quaking Grass
Banyan
Brahmi
Borassus Palm
Borassus aethiopum
Bupleurum
Centella triterpenes
Chinese Silkvine
Clary sage
Clerodendrum trichotomum
Cactus
Cyathula
Citron
Carry Me Seed
Cannabinol
Cymbopogon Martini
Calea zacatechichi
Centella asiatica
Capitate Valerian
Corktree
Cowslip
Cannabidiol
Calamus
Cherimoya
Corydalis
Carthamus
Clerodendrum indicum
Dragonhead
David's Milkberry
Doxylamine succinate
European Elder
Erodium cicutarium
Elk antler
Elephant's Head
Embelia
Flueggea suffruticosa
Ficus religiosa
Ficus simplicissima
Fringed Pink
Frankincense
Gelsemium
Geraniol
Giant Blazingstar
Glycine
Gardenia jasminoides
jasmine
Lotus
Lily
Little ironweed
Mallow
Milk Protein
Mimosa
Orchid
Poppy
Rose
Spikenard
Sandalwood
Sumac
Sweet Orange alcohol
Vervain
walnut
Other health conditions supported by Premna
Abdominal PainAntibiotics (alternatives to)
Arthritis
Asthma
Backache
Bladder Infection
Boils
Bronchitis
Bruises (healing)
Canker Sores
Cough (general)
Cuts
Diarrhea
Digestion (poor)
Dyspepsia
Eczema
Fever
Gastritis
Glands (swollen lymph)
Hair (loss or thinning)
Headache (general)
Headache (sinus)
Headache (tension)
Infection
Infection (bacterial)
Infection (viral)
Inflammation
Influenza
Insomnia
Jaundice (adults)
Kidney Infection
Liver Detoxification
Muscle Tone (lack of)
Nervousness
Pain (general remedies for)
Phlebitis
Pneumonia
Rashes and Hives
Sinus Infection
Skin (infections)
Sleep (restless and disturbed)
Sore Throat